Tag: Parkinson's

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Health

Coffee…for diabetes, Parkinson’s, liver and more?

I love my morning coffee, so I “perk up” whenever I see a study that suggests this habit is a good thing! Are you a coffee lover too? Then read on…

Overall, coffee drinkers were found to have more health benefits than risks from their habit, compared to those who did not drink any coffee. The average daily intake in those who were studied was 3 to 4 cups per day compared to no coffee daily, although some studies looked at how health changed in the years after people increased or decreased their coffee intake by a cup or two.

5 Benefits of coffee

  1. Coffee and diabetes—a 2014 study followed over 123,000 people for 4 years. Those who increased their daily coffee intake by 1 cup per day had an 11% lower chance of developing Type 2 diabetes. Those who decreased their coffee consumption (by an average of 2 cups per day) had a 17% higher risk for Type 2 diabetes. Changes in tea drinking were not linked to diabetes risk.

  2. Coffee and Parkinson’s disease—Several studies suggest that caffeine, whether in coffee or other drinks, may help decrease risk of developing Parkinson’s. One analysis determined that men who drink 4 or more coffees per day may have 1/5 the risk of those who do not. Another study in 2012 suggests that the caffeine in coffee may help control movement in people with Parkinson’s. Another study in 2017, that found a link between coffee intake and Parkinson’s, also noted coffee drinkers may be less likely to develop depression and dementias like Alzheimer’s as well. However, there wasn’t evidence to show that drinking decaf coffee would help prevent Parkinson’s.

  3. Coffee and liver diseases—Researchers in Italy found that coffee decreases risk of liver cancer by about 40%. Their numbers suggest those who drink 3 cups a day may have 50% decreased risk of liver cancer. A different literature review in 2019 concluded that “coffee intake probably reduces the risk of liver cancer”. Another large analysis in 2017 found coffee also appeared to decrease risk of non-alcoholic fatty liver disease and cirrhosis, as well as liver cancer.

  4. Coffee and heart health—We often think negatively of coffee when it comes to heart health, since people are advised not to drink it just before measuring their blood pressure. But drinking coffee in moderation, two 8-ounce servings per day, may protect against heart failure (when the heart can’t pump enough blood to meet the body’s needs), according to a 2012 study. They found an 11% lower risk of heart failure in those who drank this moderate amount versus those who drank none. Another analysis in 2017 found that those who drank 4 to 6 cups of either caffeinated or decaf coffee daily appeared to have a lower risk of Metabolic Syndrome—in other words, they had lower blood pressure, lower blood cholesterol, and lower blood sugar—and this included a decreased occurrence of Type 2 diabetes.

  5. Overall health—An umbrella study in 2017, using combined data from 218 other analyses of studies, found coffee consumption seems generally safe within usual daily amounts. It showed the largest risk reduction in those who drank 3 to 4 cups daily and that coffee is more likely to benefit health than harm it. Mortality from any cause was reduced by 17% in these coffee drinkers.

An exception to the benefit of coffee is during pregnancy, when drinking more coffee could result in low birth weight of the baby (31% greater relative risk), increased risk of pregnancy loss (an increase of 46%) and increased chance of preterm birth (12-22%). Another exception is for women at risk of bone fractures (but not men for some reason…). Increased coffee was associated with an increased risk of breaking a bone only in women. Their recommendation was for women already at risk of a bone fracture to avoid coffee.

So, I guess I can happily continue my morning coffee—no risk of pregnancy for me and my risk of bone fracture is low! I usually enjoy 3 cups as I peruse the morning news and emails, and check Facebook for photos of what my wonderful granddaughters are up to! Hmmm…must be time for cup #3…

PLEASE NOTE: A little clarification on the numbers in this blog. The percentages in this article are “relative risk” numbers not overall risk. They compare risk with the factor to risk without it. For example, a relative risk increase of 50% could mean 10% without the risk factor have the condition compared to 15% with it…or 0.01 vs 0.015%. “Actual risk” numbers were not quoted in my references, only the percentage increase in risk.)

References:

Health benefits and risks of drinking coffee https://www.medicalnewstoday.com/articles/270202.php#benefits

Changes in coffee intake and subsequent risk of type 2 diabetes: three large cohorts of US men and women https://link.springer.com/article/10.1007%2Fs00125-014-3235-7

Coffee consumption and health: umbrella review of meta-analyses of multiple health outcomes https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696634/

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Uncategorized

Is it Alzheimer’s, Parkinson’s or NPH?

NPH, Normal Pressure Hydrocephalus, is a brain disease that is often misdiagnosed because it mimics other brain conditions. This can result in patients waiting years to receive a treatment that could give them significant improvement… or never receiving it at all.

It is estimated that 15,000 Canadians and 700,000 Americans have NPH but less than 20% are diagnosed correctly. Instead, they are diagnosed with Alzheimer’s or Parkinson’s Disease, or just old age.

“Hydrocephalus” means increased water or fluid in the brain. This condition can also occur in children, but they usually have increased pressure in the brain while adults with the condition have pressure that fluctuates from normal to elevated. It is treated by surgically inserting a shunt to drain fluid from the brain and spinal cord (called cerebrospinal fluid) into another part of the body.

Adults produce 500 ml (2 cups) of cerebrospinal fluid each day. This fluid supports and cushions the brain, removes waste and distributes important substances. When its circulation is blocked, fluid accumulates, causing the cavities within the brain (called ventricles) to enlarge, pressing on parts of the brain and causing malfunction. The type of malfunction would depend on which area was receiving pressure.

Symptoms

The adult version of the disease, Normal Pressure Hydrocephalus, was named before newer forms of brain monitoring showed that pressure could be high as well as normal, but the name stuck even though it isn’t quite accurate. NPH most commonly occurs in adults over age 60. Symptoms include:

  • Difficulty standing and walking, a shuffling gait

  • Impaired bladder control

  • Memory problems and lack of concentration

It is not necessary to have all 3 symptoms to be diagnosed with NPH. In many cases, physical symptoms appear first, followed by mental symptoms like forgetfulness.

Cause

Most cases of NPH are “idiopathic”, which means the cause is unknown. This is also referred to as “primary NPH”. There is also “secondary NPH” that is caused by another condition, such as head injury, brain surgery, subarachnoid hemorrhage (bleeding in the brain), tumors, cysts (closed, sac-like abnormal structures that contain fluid, air or a semisolid substance), meningitis or other brain infections.

Symptoms progress with time. The longer and more severe the symptoms, the less likely treatment will be successful, but some patients with symptoms for years can improve with treatment. One study found that 87% of those treated had experienced improvement.

How is it diagnosed?

Often the affected person or a family member brings the symptoms to the attention of the family doctor, leading to a diagnosis. Sometimes enlarged ventricles (fluid-filled spaces) in the brain are found when the brain is scanned for another reason. It is recommended to see a neurologist or neurosurgeon if NPH is suspected for an evaluation and interpretation of test results.

3 types of testing can be used:

  1. An interview, physical exam (to rule out other causes) and a neurologic exam to assess brain function

    1. Observation of walking and turning

    2. Questions about bladder function

    3. Pencil and paper tests to examine attention, reaction time, memory, reasoning, language and emotional state).

  2. Brain imaging to look for enlarged ventricles in the brain

    1. CT scan

    2. MRI (can detect impaired fluid flow as well as enlarged ventricles)

  3. Tests to predict whether surgery will help

    1. Lumbar puncture/spinal tap (A thin needle is inserted into the fluid around the base of the spine in the lower back. Pressure can be tested and up to 50 ml of fluid is drained off to see if lowering fluid pressure will improve symptoms)

Because of the high rate of misdiagnosis, the Hydrocephalus Association is conducting a campaign to inform doctors and the public about NPH. Check out their website — it’s a good place to start, if you are interested in more information.

References:

CTV News

The Hydrocephalus Association